The UCI Experimental Pathology Graduate Training Program is part of the large, multidisciplinary Graduate Program in Cellular and Molecular Biosciences. The Experimental Pathology Training Program functions as an area of study within the larger program, sharing a common core curriculum and admissions process. Pathology is the study of diseases and disease processes. The Experimental Pathology faculty investigate molecular mechanisms that underlie diseases which affect specific organ systems. Studies deal with 1) the etiology, or specific molecular and cellular defects that cause human diseases, and 2) pathogenesis, or the mechanisms that result in the presenting signs and symptoms associated with disease conditions. Our goals are to provide instruction that illustrates those mechanisms and considers hypothesis-based approaches to their analysis.
The recommended curriculum draws from the classic and emerging literature to illustrate mechanisms of disease. There is strong emphasis on a critical appraisal of the strengths and limitations of experimental approaches and the diverse animal models used in disease research. The research interests of Experimental Pathology faculty includes varied topics that are broadly grouped under the headings: Acquired Immune Deficiency Syndrome (AIDS), developmental neurobiology and cardiology, ion channels, immunopathology, and mechanisms of cell signaling and cancer. Recognizing these diverse research interests, the suggested curriculum for students considering the track is broadly-based. A combination of electives are offered that provide a research-oriented consideration of etiology and pathogenesis, including short 1-4 unit courses that focus on specific topics in pathobiology. Didactic teaching components of students in the group are supplemented by tutorial and research conferences in which graduate students and postdoctoral fellows gain experience by presenting original data in research seminars and insight from diverse scientific viewpoints. Student fellowship opportunities are available through several NIH-sponsored training grants.
Full Experimental Pathology Faculty Listing
