Wei Li
Computational Biomedicine: Epigenetics Liquid Biopsy and Alternative Polyadenylation Therapy
Our research seeks the mechanisms that underlie neurodegeneration and neuron cell death in spinal & bulbar muscular atrophy, spinocerebellar ataxia
Regulation of gene expression by alternative splicing, bioinformatics, human genetic disease
Prostate cancer disparities, ovarian cancer, cervical cancer, bioinformatics, epigenetics
Cancer etiology, cancer genetics, genome integrity, DNA double-strand break repair, and cancer health disparities in underrepresented groups
Unannotated microprotein discovery and characterization, proteomics, genomics, cell biology, protein biochemistry
Nutritional microenvironment in tumor development and drug response, metabolism, epigenetics and cancer stem cells, protein phosphatase regulation in diabetes and
Our lab studies the ubiquitin proteasome pathway, cell cycle, and cancer metabolism, focusing on mechanism of diet/therapeutics interactions and development
My laboratory is focused on the biology of endocrine pancreatic cells, which synthesize and secrete the principal hormones that regulate
Identifying therapeutic vulnerabilities in solid malignancies harboring RB1 mutations, with special emphasis on epigenetics.