The rise of affordable sequencing technologies is revolutionizing all areas of biology. This is most evident in the areas of areas of genetics, epigenetics, and genomics, where a number of faculty across the school of biological sciences and the medical school use genome-wide techniques to study gene regulation in development and disease, comparative genomics, the connection of epigenetic changes to metabolism, and cellular decision-making. Participants in this track benefit from interactions with students and faculty from UCI’s strong systems biology and modeling program as well as from workshops organized by the UCI Genomics High Throughput Facility.
The Genetics, Epigenetics, and Genomics program at UCI provides research training on the latest genome-wide techniques to study protein-DNA interactions, RNA expression, open chromatin, and long-range interaction in functional genomics, and personalized medicine. Students from this track will take graduate coursework in genetics and genomics while rotating through multiple laboratories to indentify research topics of interest to them, which can span all of the areas of the CMB program in cell, developmental, cancer, immunology, and genetics with the emphasis on genome-wide analysis projects.
- Steve Allison, firstname.lastname@example.org, Ph.D., Associate Professor, Ecology & Evolutionary Biology
Microbial enzymes, theoretical ecology, and biogeochemistry.
- Bogi Andersen, email@example.com Ph.D., Professor of Medicine and Biological Chemistry
Transcriptional regulation in the developmental biology of epidermis and mammary gland
- Tallie Z. Baram, firstname.lastname@example.org, M.D., Ph.D, Professor of Anatomy & Neurobiology and Physiology & Biophysics
Epigenetic mechanisms in brain plasticity; stress, epilepsy, learning and memory
- Emiliana Borrelli, email@example.com Ph.D., Professor of Microbiology & Molecular Genetics
Dopaminergic system and glial cells in CNS development
- J. Jay Gargus, firstname.lastname@example.org, M.D., Ph.D., Professor of Physiology & Biophysics and Pediatrics
Molecular analysis of membrane signaling proteins
- Brandon Gaut, email@example.com, Ph.D., Professor of Ecology & Evolutionary Biology
Population genetics, molecular evolution, genome evolution.
- Klemens Hertel, firstname.lastname@example.org Ph.D., Professor of Microbiology & Molecular Genetics
Regulation of gene expression by alternative splicing
- Haoping Liu, email@example.com, Ph.D., Associate Professor of Biological Chemistry
MAP kinase signal transduction; dimorphic regulation in yeast.
- Jennifer B.H. Martiny, firstname.lastname@example.org, Ph.D., Professor of Ecology & Evolutionary Biology
Diversity, evolution, and functioning of microbial communities (microbiomes).
- Ali Mortazavi, email@example.com, Ph.D., Associate Professor of Developmental & Cell Biology
Applications of genomics, computation, and sequencing technologies to the analysis of transcriptional regulation in development.
- R. Michael Mulligan, firstname.lastname@example.org, Ph.D., Professor of Developmental & Cell Biology and Ecology & Evolutionary Biology
RNA editing in plant mitochondria and chloroplast
- Feng Qiao, email@example.com, Ph.D., Associate Professor of Biological Chemistry
Telomeres & telomerase and their roles in cancer and stem cell diseases; Structural, biochemical and molecular genetic analyses of nucleoprotein assemblies
- Jose M. Ranz, firstname.lastname@example.org, Ph.D., Assistant Professor of Ecology & Evolutionary Biology
Functional and comparative genomics; Evolution of the expression network; Speciation.
- Suzanne B. Sandmeyer, email@example.com, Ph.D., Professor of Biological Chemistry
Molecular genetics of a position-specific yeast retrovirus-like element
- Paolo Sassone-Corsi, firstname.lastname@example.org Ph.D., Distinguished Professor and Chair of Pharmacology
Mechanisms of gene expression and epigenetics
- Yongsheng Shi, email@example.com, Ph.D., Associate Professor of Microbiology & Molecular Genetics
The role of post-transcriptional gene regulation in stem cells and cancer
- Sha Sun, firstname.lastname@example.org, Ph.D., Assistant Professor of Developmental & Cell Biology
Long noncoding RNAs in epigenetic programming
- Ping Wang, email@example.com, M.D., Professor of Medicine, Biological Chemistry, Physiology & Biophysics, and Pathology & Laboratory Medicine
Molecular hormone actions in diseases and stem cells
- Katrine Whiteson, firstname.lastname@example.org, Ph.D., Assistant Professor of Molecular Biology & Biochemistry
Metagenomics, metabolomics and community culture models of host-associated microbial and viral communities in health and disease; human microbiome; microbial ecology.
- Zeba Wunderlich, email@example.com, Ph.D., Assistant Professor of Developmental and Cell Biology
Experimental and computational approaches to understanding regulatory DNA in animals.
- Xiaohui Xie, firstname.lastname@example.org Ph.D., Professor of Computer Science and Developmental & Cell Biology
Computational biology, bioinformatics, and genomics
- Qin Yang, email@example.com, Ph.D., Assistant Professor of Medicine and Physiology & Biophysics
Cellular and molecular mechanisms for insulin resistance and energy expenditure in obesity and type 2 diabetes
- Kyoko Yokomori, firstname.lastname@example.org Ph.D., Professor of Biological Chemistry
Molecular mechanisms of chromosome dynamics and gene regulation
- Michael Zaragoza,,email@example.com M.D., Ph.D., Assistant Professor of Biological Chemistry and Pediatrics
Molecular mechanisms of inherited cardiovascular diseases
Faculty – Secondary Affiliation
- Claudia Benavente, firstname.lastname@example.org, Ph.D., Assistant Professor of Developmental & Cell Biology
Understanding epigenetic deregulation in pediatric cancer tumorigenesis
- Bruce Blumberg, email@example.com, Ph.D., Professor of Developmental and Cell Biology
Gene regulation by nuclear hormone receptors in vertebrate development and adult physiology
- Anne L. Calof, firstname.lastname@example.org, Ph.D., Professor of Anatomy & Neurobiology and Developmental & Cell Biology
Regulation of stem cells in development and regeneration; genomic strategies for understanding the etiology and treatment of human neurodevelopmental disorders using transgenic mouse models
- Jefferson Y. Chan, email@example.com, M.D., Ph.D., Professor of Pathology & Laboratory Medicine
Regulation of genes associated with oxidative stress
- Xing Dai, firstname.lastname@example.org, Ph.D., Professor of Biological Chemistry
Skin and mammary stem cells, Wnt signaling, chromatin, transcription
- Robert Edwards , email@example.com M.D., Ph. D., Associate Professor of Pathology & Laboratory Medicine, In Residence
Pathogenesis of inflammatory bowel disease
- Peter Kaiser, firstname.lastname@example.org, Ph.D., Professor of Biological Chemistry
Cell cycle control; regulation of proteins by ubiquitination
- Selma Masri, email@example.com, Ph.D., Assistant Professor, Biological Chemistry
Cancer Biology, Circadian Rhythms, Epigenetics and Metabolism.
- Leslie M. Thompson, firstname.lastname@example.org, Ph.D., Professor of Psychiatry and Biological Chemistry
Molecular and biochemical mechanisms of disease pathogenesis and therapeutic approaches to human neurodegenerative disease
- Rahul Warrior, email@example.com, Ph.D., Associate Professor of Developmental & Cell Biology
Developmental regulation of proteoglycan biosynthesis; Transcriptional response to BMP growth factor signaling