Research opportunities in cancer biology span a broad spectrum.  They include studies on fundamental biological processes involved in the development of cancer (e.g. oncogenes and tumor suppressor genes, tumor virology, signal transduction, cancer genetics, growth factors, cancer immunology, structural analysis) and in diagnosis or therapy of cancer (e.g. chemoprevention, gene therapy, tumor imaging).  Experimental systems range from simple eukaryotes such as yeast, through Drosophila and mice to humans.

Students in Cancer Biology are eligible for support from an NIH training grant in Cancer Biology and Therapy.  A variety of national and international meetings on cancer-related topics are organized by the UCI Cancer Research Institute, and they provide opportunities for learning about the most recent developments in cancer research.  The UCI Chao Family Comprehensive Cancer Center (a National Cancer Institute-designated comprehensive center) also provides opportunities for students to interact with clinicians engaged in research and treatment of cancer patients.

Focus Area Coordinator:  Marian L.


Faculty – Secondary Affiliation

  • Bruce Blumberg,, Developmental and Cell Biology
    Gene regulation by nuclear hormone receptors in vertebrate development and adult physiology
  • Dae Seok, Developmental & Cell Biology
    Specialized cellular projection-mediated cell-to-cell signaling
  • Klemens Hertel,, Microbiology & Molecular Genetics
    Regulation of gene expression by alternative splicing
  • Lan Huang,, Physiology & Biophysics and Developmental & Cell Biology
    Proteomics analysis using mass spectrometry and bioinformatics to elucidate protein structure and function, with initial emphasis on the 26S proteasome functional specificity
  • Chang Liu,, Biomedical Engineering, Chemistry, and Molecular Biology & Biochemistry
    Engineered genetic systems for rapid evolution, chemical biology, synthetic biology, and cell biology
  • Melissa Lodoen,, Molecular Biology & Biochemistry
    Modulation of host immunity by Toxoplasma gondii
  • Naomi Morrissette,, Molecular Biology & Biochemistry
    Genetic, cell biological and structure-function studies of tubulin and microbutules in Apicomplexan parasites
  • Jennifer Prescher,, Chemistry, Molecular Biology & Biochemistry, and Pharmaceutical Sciences
    Probing biological systems with chemical tools and noninvasive imaging
  • Sha Sun,, Developmental & Cell Biology
    Long noncoding RNAs in epigenetic programming
  • Ming Tan,, Microbiology & Molecular Genetics, and Medicine
    Chlamydia infections: Gene regulation and host pathogen interactions
  • Francesco Tombola,, Physiology and Biophysics
    Molecular mechanisms of coltage-gated ion channel function
  • Gregory A. Weiss,,  Chemistry and Molecular Biology & Biochemistry
    Using molecular evolution in a test tube (phage display) to explore the chemistry and biology of cells
  • Qin Yang,, Medicine and Physiology & Biophysics
    Cellular and molecular mechanisms for insulin resistance and energy expenditure in obesity and type 2 diabetes
  • Kyoko Yokomori,, Biological Chemistry
    Molecular mechanisms of chromosome dynamics and gene regulation