John Chaput
Oligonucleotide therapeutics based on evolvable non-natural genetic polymers
We study the human fungal pathogen Candida albicans, Candida-host cell interaction, mechanisms of pathogenesis and drug resistance.
Bioinformatics; genetic factors in human diseases; medical, environmental and marine genomics; computational drug discovery; machine learning
The Marazzi Laboratory studies epigenetic and chromatin-mediated control of gene expression in the context of the cellular response to pathogens
The Sun Laboratory studies genetic mechanisms of skin tissue development and disease with a particular interest on regulatory elements of
Molecular and biochemical mechanisms of disease pathogenesis and therapeutic approaches to human neurodegenerative disease
Intrinsic and microenvironmental control of skin and mammary epithelial stem cell function in development and repair/regeneration, and how such control
The goal of my research is to understand the role of the circadian clock in skin and the gene-regulatory mechanisms